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Whereas Dupuytren's disease affects the palm of the hand, Ledderhose disease affects the sole of the foot. The two are so closely linked that a famous hand surgeon named Hueston stated that, “The first clinical examination of every patient with Dupuytren's disease must involve removal of the patient's shoes.” (Hueston, J. (1990). Dupuytren’s diathesis. In: Dupuytren’s Disease Biology and Treatment. R.M. McFarlane, D. McGrouther, and M.H. Flint, eds. (Churchill Livingstone), pp. 246–252.)
Most people with Ledderhose disease don’t know that they have it – at least at first.
Normally, the first inkling of the disease is distention or swelling in the sole of the foot that is painful when it pressed against a shoe or the ground. The pain may be severe enough to discourage you from walking – and later, make walking impossible.
For this combination of reasons – absence of pain at first, then rather sudden pain as the swelling reaches a size large enough to touch the shoe or the floor – many people get the impression that the disease has popped full-grown from nowhere.
The swelling, which gradually becomes a lump, typically appears in the middle of the sole, often in the arch of the foot, but also in the toes and sometimes in the heel or side of the foot.
The lumps are usually slow-growing and generally less distinct and less easily palpated than those of Dupuytren's disease. Pitting is not seen, and, unlike in Dupuytren's disease, the overlying skin is freely movable.
Ledderhose disease, which affects about 1 in 5 older people of European descent, is less common than Dupuytren's disease. People with Dupuytren’s disease are quite likely to have Ledderhose disease.
Ledderhose disease resembles Dupuytren's disease in that it is different in every person with the disease but is unlike it in that it is less frequently (though unfortunately still rather often) bilateral.
In most cases the disease never bothers the person, persisting as rather indistinct lumps that may or may not be tender.
Sometimes previously painless lumps become tender and may make walking and standing painful, in some unfortunate people to the point that they cannot stand or walk.
Only rarely does the disease cause cords to form or the toes to contract.
Its progress is impossible to predict, often remaining static but sometimes, without warning, developing quickly.
Most cases of Ledderhose disease manifest as lumps near the inner edge of the sole, at the highest point of the arch. In rare cases, however, Ledderhose disease has been reported in the side of the foot and ankle.
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Contact information provided below for radiation oncologists who have treated for Dupuytren's Contracture or Ledderhose . Comments or opinions expressed here or on DART are not intended to diagnose or prevent disease. Advice or comments should not be relied upon unless confirmed by your treating physician. No doctor-patient relationship is intended and members are advised to consult their doctors for medical advice. No representation is made about the quality or professional competency of the listed doctors. This listing provided as a place for you to begin your own research. If you find the contact info outdated or in error, please comment on DART where it can be corrected. You might also google the doctor or clinic to find updated contact information. Many of these doctors also practice at secondary locations that may be closer to you. Check their website. In addition to their clinical practice, many of these radoncs are also on the faculty of local medical schools where they teach radiation oncology. If you have doctor or clinic information not listed below, please share with DART so it can be made available to others looking for treatment in that location. some photos from dupuytrens.org Thank you.
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